Factors Affecting Effectiveness of Fecal Microbiota Transplant

Factors Affecting Effectiveness of Fecal Microbiota Transplant

Fecal Microbiota Transplant: Benefits and Risks

We commend the authors of “Weight Gain After Fecal Microbiota Transplantation” for describing this case of obesity after a fecal microbiota transplant (FMT). Fecal microbiota transplant is a highly effective therapy for recurrent Clostridium difficile infection (r-CDI), and the authors discuss possible unintended consequences in a patient after successful FMT, which could be due to alteration o...

Microscopic Colitis After Fecal Microbiota Transplant

Microscopic colitis (MC) is an inflammatory condition of the large bowel that is associated with chronic, nonbloody diarrhea. Colonoscopy usually demonstrates normal mucosa, while tissue biopsy reveals intraepithelial lymphocytes or a subepithelial collagen band. Although no specific antibody has been discovered, MC is associated with several autoimmune disorders such as celiac disease, Hashimo...

Clostridium difficile Infection and Fecal Microbiota Transplant.

Clostridium difficile infection (CDI) is a major source of morbidity and mortality for hospitalized patients. Although most patients have a clinical response to existing antimicrobial therapies, recurrent infection develops in up to 30% of patients. Fecal microbiota transplant is a novel approach to this complex problem, with an efficacy rate of nearly 90% in the setting of multiple recurrent C...

Cost-Effectiveness of Fecal Microbiota Transplant in Treating Clostridium Difficile Infection in Canada.

Figure 1: Model of CDI transmission across three major subpopulations Objectives: To estimate the cost-effectiveness of Fecal Microbiota Transplant (FMT) for Clostridium difficile infection (CDI) as compared to current practice comprising of antibiotic treatments. Methods: We developed a decision analytic model to compare strategies for the management of CDI, by age, gender, and three major sub...